The Technological Response to a Global Pandemic
summary
The Francis Crick Institute repurposes labs into a COVID 19 diagnostic centre and within two weeks fields a high-throughput RT‑PCR pipeline integrated with HSL UCLH and ICR, using barcode tracking, SFTP order files, a Hamilton liquid handler for 96‑well RNA extraction, QuantStudio PCR, MySQL/Postgres backends and a Python Django bespoke web app. The system processes about 150,000 samples to date with a two-step reporter check and achieves <24-hour turnaround for 95% of samples, demonstrating a working, auditable end-to-end pipeline.
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chapters (9)
- 0:00The technological response to a global pandemic The Francis Crick Institute COVID19 consortium diagnostic pipeline.
- 2:04The Crick in numbers
- 4:16"Discovery without boundaries" 7 Core research areas: • Growth and development • Health and ageing
- 10:08Challenge: How to extend testing access? Solution: Work with HSL to interface with existing systems one size does NOT fit all!
- 12:30Crick Sample tracking pipeline (simplified!)
- 15:12COVID-19 PCR pipeline - sample tracking & reporting
- 20:44In-house Technology under the hood
- 22:52Current status and Future plans
- 24:14Additional information
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