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Managed federated learning on AWS: A case study for healthcare

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Reproduces federated training on eICU (200k stays, ~200 hospitals) to predict in‑hospital mortality, compares centralized vs federated runs, and evaluates open source stacks (TensorFlow Federated, PySyft/PyGrid, FedML). Implements FedML on AWS with VPC peering and gRPC for cross‑silo experiments, uses custom partitioned data loaders, and tracks per‑round bytes, rounds, and AUC/loss. Notes operational gaps: orchestration, instance sizing, decentralized logging and debugging, and privacy needs addressed via differential privacy and secure aggregation; centralized AUC ~0.89, federated ~0.88.

AI-written summary · about

  1. 0:00Intro
  2. 1:31Team
  3. 5:26Privacy-preserving federated learning (PPFL)
  4. 10:38What makes this hard to run on AWS?
  5. 14:16Need for generalizability in healthcare models
  6. 21:20Important criteria for selecting FL frameworks
  7. 23:16TensorFlow Federated
  8. 28:37FedML architecture
  9. 29:49System architecture
  10. 31:39Prerequisites Single account - multiple instances Instances
  11. 32:24Multiple accounts: Cross-silo FL clients with multi-GPU distributed training
  12. 35:27What you will see
  13. 42:57Evaluation metrics: Performance metrics
  14. 43:15Evaluation metrics: Model metrics
  15. 44:01Acknowledgments
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