Slush Science Pitching Finals 2017: Olli Karkkainen
summary
A project using metabolic profiling of hundreds of small molecules aims to predict which adolescents will develop alcohol use disorder and who will respond to specific medications. A pilot study exists and the next phase is recruiting 500 participants with plans for separate discovery and confirmation cohorts. The claim is that longitudinal shifts in metabolite patterns correlate with brain changes and later problematic drinking, enabling targeted early prevention rather than broad treatment for all.
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