~/talk

The Copy Number Transformation Problem

Talkat Computational Cancer Biology 2016 · 2016-02-01..02-05
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slides:none on file

Defines copy-number profiles as integer vectors and operations as unit ±1 operations on contiguous intervals; proves each position needs at most max copy number N edits and shows deletions can be pushed early under the model. Builds a dynamic programming table over indices and edit counts, then compresses rows into piecewise-linear functions so the optimal distance and an optimal transformation are computable in linear time using constant space.

AI-written summary · about

  1. 0:00Start
  2. 0:26Copy Numbers (CN)
  3. 2:55Problem Statement
  4. 4:45Key Propositions (Informal)
  5. 7:58Dynamic Programming
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