Accelerating privacy-enhancing data processing
summary
Shows a concrete pipeline that turns messy hospital records (free text, scanned documents, multiple standards) into research-grade datasets by chaining an extract/normalize/load library into a warehouse, SQL transforms and post-DB NLP, all orchestrated without heavy infra. Uses Dexter, dbt and DT with Ibis and Snowflake (or DuckDB for local/hospital runs), cuts warehouse costs by ~50%, supports NLP/OCR harmonization, implements consent/deletion bookkeeping, and surfaces results used in ~1,200 publications and ~9,000 citations.
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chapters (11)
- 0:00Introduction and agenda
- 1:52What is real world evidence
- 5:26Challenges in data integration
- 7:33Data architecture overview
- 10:22Feedback loops in data systems
- 13:05Technology stack overview
- 20:53Building the data pipeline
- 29:43Patterns to accelerate feedback loops
- 31:48Making pipelines portable
- 35:44Impact on cancer research
- 37:11Q&A session
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