Big data, AI, the genome, and everything
summary
A real case shows rapid sequencing saving a life after cerebrospinal fluid DNA pinpointed an obscure bacterial infection. DNA sequencing cost falls from ~$10 million (2007) to under $1,000 today and genomes double every seven months, driving projected storage needs of 2–40 exabytes/year by 2025. Alignment speed improves with SNAP alignment (7× faster than common algorithms). Gene editing uses Cas9 with ~18 billion guide RNA combinations across ~20,000 genes; CRISPR ML on the Azure cloud yields ~20% better targeting and ~50% lower time and cost per gene.
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chapters (4)
- 0:00Start
- 4:23Major Generators of Big Data
- 9:00Virtuous Cycle for Genomics and Al Genomics
- 9:29Gene Editing Knockout a Gene
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