EXSCALATE: Building a Faster, More Efficient & Less Costly Drug Discovery Platform with MariaDB
summary
EXSCALATE is a supercomputing drug‑discovery pipeline built around the TCS DB, the world’s largest enumerated chemical library, using MariaDB ColumnStore to store and query tens of millions of in‑silico molecules for docking, simulation and AI screening. The stack runs on HPC, combines physics‑based simulation with ML models, and reports about 70% storage savings versus previous setups plus a clear cost advantage in the MariaDB‑to‑Oracle comparison, enabling faster, cheaper candidate selection.
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chapters (7)
- 0:00Start
- 0:30Intro
- 0:54The drug discovery business challenge
- 5:26HPC Chapter Heading 2 (with timecode hyperlink)
- 7:34Role of Data and Database in drug discovery
- 9:59Solution Architecture
- 11:32Cost comparison of MariaDB to Oracle
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